Patrícia Silva, PhD, director of science content —

The ALS Association together with the ALS Finding a Cure Foundation recently announced a $3 million funding for two Phase II clinical trials via the ALS Accelerated Therapeutics (ALS ACT) initiative, a project focused on accelerating the discovery of new ALS therapies in part by funding pilot clinical…

Genervon Biopharmaceuticals recently announced it has filed a patent application based on data from the Phase 2A clinical trial (GALS001 study, NCT01854294) assessing the company’s product GM604 as a therapy for amyotrophic lateral sclerosis (ALS) and data from a single ALS compassionate patient study (GALS-C). ALS is a…

Researchers at the University of California at San Francisco (UCSF) recently revealed new insights into the pathogenesis of neurodegenerative diseases. The study, published in The Journal of Neuroscience, is entitled “The Progranulin Cleavage Products, Granulins, Exacerbate TDP-43 Toxicity and Increase TDP-43 Levels”. Mutations in…

The ALS (amyotrophic lateral sclerosis) Association revealed that a team of researchers funded by the Association and led by Dr. Timothy Miller and Dr. Randall Bateman from Washington University in Saint Louis, recently discovered important insights into the ALS-related protein called copper (Cu)/zinc (Zn) superoxide dismutase (SOD1). ALS…

Researchers at CRCHUM and the University of Montreal in Canada discovered a previously unknown link between amyotrophic lateral sclerosis (ALS) neurodegeneration and the immune system. The study was recently published in the journal Nature Communications and is entitled “Neurodegeneration in C. elegans models…

Dr. Ivan Dikic at Goethe University, Frankfurt, Germany has been involved in two groundbreaking studies focusing on molecular details underlying neurodegenerative diseases. The studies were conducted by international research teams and were recently published in the journals Nature Neuroscience – “Haploinsufficiency of TBK1 causes familial…

A new study recently published in the journal PNAS revealed that a new cellular mechanism involving a key protein called hUPF1 can be exploited as a therapeutic strategy for amyotrophic lateral sclerosis (ALS). The study is entitled “Amelioration of toxicity in neuronal models of…

A new study entitled “Syringe-injectable electronics” recently published in the journal Nature Nanotechnology revealed an innovative method to employ tiny electronic devices in the brain, or other parts of the body, as a potential therapy for a wide range of disorders, including neurodegenerative diseases…

Q Therapeutics, Inc., a company focused on adult stem cell therapies for disorders of the central nervous system, recently announced that its product Q-Cells® has received Investigational New Drug (IND) clearance by the U.S. Food and Drug Administration (FDA) for the start of Phase 1/2a clinical trials in…

Sigma-Aldrich Corporation recently announced it has established an agreement with XCell Science to launch genetically engineered human neural differentiated cells and the corresponding culture media to advance research in the neurological diseases field. Together with the product portfolio of Sigma-Aldrich, these new products offer unique tools relevant for the…